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David J Hughes Selected Research

3-Phosphoinositide-Dependent Protein Kinases

11/2017Dysregulation of KRAS signaling in pancreatic cancer is not associated with KRAS mutations and outcome.

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David J Hughes Research Topics

Disease

25Neoplasms (Cancer)
06/2022 - 03/2007
25Colorectal Neoplasms (Colorectal Cancer)
06/2022 - 06/2010
9Infections
01/2022 - 10/2004
6Carcinogenesis
06/2022 - 10/2018
5Adenoma (Adenomas)
06/2022 - 04/2015
5Virus Diseases (Viral Diseases)
01/2021 - 02/2011
4Inflammation (Inflammations)
12/2021 - 01/2021
3Hypoxia (Hypoxemia)
06/2022 - 11/2009
3Breast Neoplasms (Breast Cancer)
12/2007 - 11/2005
2Colonic Neoplasms (Colon Cancer)
01/2021 - 12/2018
2Drug-Related Side Effects and Adverse Reactions
01/2021 - 01/2017
2Hepatocellular Carcinoma (Hepatoma)
02/2017 - 01/2016
2Liver Neoplasms (Liver Cancer)
02/2017 - 01/2017
1COVID-19
01/2022
1Chronic Disease (Chronic Diseases)
12/2021
1Dysbiosis
01/2021
1Prostatic Neoplasms (Prostate Cancer)
01/2021
1Metabolic Syndrome (Dysmetabolic Syndrome X)
04/2020
1Obesity
04/2020
1Latent Infection
01/2020
1Paramyxoviridae Infections (Parainfluenza)
01/2019
1Thymoma (Thymic Carcinoma)
11/2017
1Adenocarcinoma
11/2017

Drug/Important Bio-Agent (IBA)

14Proteins (Proteins, Gene)FDA Link
01/2021 - 11/2005
12SeleniumIBA
06/2022 - 06/2010
6Biomarkers (Surrogate Marker)IBA
01/2021 - 06/2010
5Selenoproteins (Selenoprotein)IBA
06/2022 - 06/2010
4Vitamin DFDA LinkGeneric
01/2022 - 09/2011
4ORALIT (ORS)IBA
01/2022 - 01/2021
4ZincIBA
01/2022 - 01/2017
4CopperIBA
01/2022 - 01/2017
4Selenoprotein PIBA
10/2021 - 03/2015
3MicronutrientsIBA
01/2022 - 02/2017
3RNA (Ribonucleic Acid)IBA
01/2021 - 06/2015
3DNA (Deoxyribonucleic Acid)IBA
10/2019 - 11/2005
3Calcitriol Receptors (Calcitriol Receptor)IBA
01/2019 - 09/2011
2Biological ProductsIBA
06/2022 - 01/2022
2Folic Acid (Vitamin M)FDA LinkGeneric
01/2022 - 01/2021
2IronIBA
01/2022 - 01/2021
2MagnesiumIBA
01/2022 - 01/2021
2Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
01/2022 - 01/2021
2VitaminsIBA
01/2022 - 01/2021
2Vitamin B 6IBA
01/2022 - 01/2021
2Phosphorus (Red Phosphorus)IBA
01/2022 - 01/2021
2CalciumIBA
01/2022 - 01/2021
2Carotenoids (Carotene)IBA
01/2022 - 01/2021
2Complement System Proteins (Complement)IBA
01/2022 - 01/2021
2Fatty Acids (Saturated Fatty Acids)IBA
01/2022 - 03/2007
2Advanced Glycation End ProductsIBA
12/2021 - 01/2021
2Pharmaceutical PreparationsIBA
01/2021 - 11/2020
2LigandsIBA
01/2021 - 01/2012
2Antiviral Agents (Antivirals)IBA
01/2021 - 01/2020
2Fluorouracil (Carac)FDA LinkGeneric
11/2020 - 01/2012
2Messenger RNA (mRNA)IBA
01/2019 - 12/2018
2MicroRNAs (MicroRNA)IBA
12/2018 - 04/2015
1Oxygen (Dioxygen)IBA
06/2022
1Volatile Fatty AcidsIBA
12/2021
12-methylbutanoic acidIBA
12/2021
1n-pentanoic acid (valeric acid)IBA
12/2021
1propionic acid (potassium propionate)IBA
12/2021
1AcidsIBA
12/2021
1Dietary Advanced Glycation End ProductsIBA
09/2021
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2021
1trovafloxacinIBA
01/2021
1ethyl lysineIBA
01/2021
1Bacteroides fragilis toxinIBA
01/2021
1Receptor for Advanced Glycation End ProductsIBA
01/2021
1Troglitazone (Rezulin)FDA Link
01/2021
1BuffersIBA
01/2021
1Digoxin (Digitek)FDA LinkGeneric
01/2021
1TamoxifenFDA LinkGeneric
01/2021
1Glyoxal (Ethanedial)IBA
01/2021
1InterferonsIBA
01/2021
1Pyruvaldehyde (Methylglyoxal)IBA
01/2021
1methyl-lysineIBA
01/2021
1Adenosine Triphosphate (ATP)IBA
11/2020
1ATP-Binding Cassette Transporters (ABC Transporters)IBA
11/2020
1Antineoplastic Agents (Antineoplastics)IBA
11/2020
1Long Noncoding RNAIBA
01/2020
1DNA-Directed RNA Polymerases (RNA Polymerase)IBA
01/2019
1Intergenic DNA (Junk DNA)IBA
01/2019
1Poly AIBA
01/2019
1hydroxide ionIBA
01/2019
1AntigensIBA
01/2019
1AntibodiesIBA
01/2019
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2019
125-hydroxyvitamin DIBA
01/2019
1Interleukin-8 (Interleukin 8)IBA
12/2018
1CytokinesIBA
12/2018
1Interleukin-6 (Interleukin 6)IBA
12/2018
1Viral ProteinsIBA
10/2018
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
11/2017
1ral Guanine Nucleotide Exchange FactorIBA
11/2017
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
11/2017
1Mitogen-Activated Protein KinasesIBA
11/2017
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
11/2017
13-Phosphoinositide-Dependent Protein KinasesIBA
11/2017
1Fatty Acid Binding Protein 3IBA
01/2017

Therapy/Procedure

2Therapeutics
11/2017 - 11/2014
1Diet Therapy (Therapy, Diet)
01/2021